Is Addiction Hereditary?

by | Last updated Feb 10, 2022 | Published on Dec 13, 2018 | Addiction Treatment, Family Recovery | 0 comments

Is Addiction Hereditary? The role of genes in drug use, dependence, and addiction

It wasn’t until the turn of the 20th century that addiction was seen as a disease rather than a moral flaw. Now, in the 21st century, the way we think about addiction is changing yet again. Recent scientific findings have revealed that genetics can play a significant role in a person’s likelihood to turn use drugs. What’s more, DNA can also influence how vulnerable a person might be to getting hooked, raising a new question: Is addiction hereditary? 

The Role Of Genetics In Drug Addiction

According to the American Psychological Association, an individual’s genetics determines their susceptibility to drug addiction by at least 50%. Despite these findings, many still doubt that genetics can inform one’s decision to take drugs. Researchers are becoming increasingly aware that the general public has a degree of distrust when it comes to genetic testing.

Despite the tremendous potential such studies can have on the efficacy of addiction treatment, only 4% of the country’s primary-care physicians are comfortable relying on genetic testing to outline a course of treatment for their patients.  Steps will need to be taken to help improve not only the public’s understanding of genetics but also physicians, says Alexandra Shields, Ph.D., director of the Harvard University/Massachusetts General Hospital Center on Genomics. As far as what steps should be taken, Shields admitted that additional research will be needed to identify ways of improving genetic testing acceptance.

Addiction Hereditary

How Genetic Testing Can Help Addiction Treatment

There have been significant advancements in genetic testing over the last few years. The scientific community is encouraging physicians to take notice, especially since these advancements could lead to improved patient care for those struggling with drugs or alcohol. For example, it’s been determined that a certain dopamine receptor in the brain has the potential to help those addicted to hard drugs. The same also holds true for those addicted to alcohol.

While tobacco is not an illicit drug, genetic testing is also being used to identify why some smokers have trouble quitting while others can quit with ease. According to Caryn Lerman, Ph.D., a psychologist at the University of Pennsylvania, genetics determines one’s dependence on nicotine by as much as 60 percent. The same data indicates that genetics determines one’s desire to starting smoking by as much as 75 percent.

Understanding Drug & Alcohol Dependence

Despite scientific data showing a nexus between drug or alcohol dependence and genetics, it doesn’t negate the fact that there are environmental factors that contribute to one’s decision to use drugs. If someone is predisposed to chemical dependency as a result of their genetics, adding environmental factors into the mix will likely contribute to their dependency.

According to the World Health Organization, more than 76 million people worldwide are addicted to alcohol.

The United Nations estimates that nearly 185 million people worldwide are taking some variation of illicit drugs. While most will agree that the cravings, anticipation, preoccupation, and the effects of withdrawal can drive one’s desire to continue taking drugs, the debate regarding whether the driving force is tied to hereditary still continues.

The scientific community remains diligent in their research, combing through data to identify how genetic testing can be better utilized to provide custom treatments for those who are alcohol or drug-dependent.

It worth pointing out that adaptive changes in gene expression in the brain occur when someone consumes illicit drugs, and these adaptive changes will often dictate tolerance, habit, and cravings. So while some may argue that drug dependence connotes a mental weakness, there is no denying that the change in brain physiology is also a factor.

It is important that we don’t demonize those who are struggling with drugs or alcohol as it may be hereditary and beyond their ability to control. Instead, we should be supportive and encourage them to seek treatment. Get help today from a local Maryland addiction treatment center.

Written by: Amanda Daniels

Written by: Amanda Daniels

Amanda Daniels is the voice behind the brand Addict Chick and the Director of Social Media for Amethyst Recovery Center.  She is a best selling author and recovering drug addict. Check out her website, or you can follow her on Facebook or Instagram.

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