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How Long Do Opioids Stay In Your System?

Amanda Stevens, B.S.

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Amanda Stevens, B.S.

On December 4, 2020

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Key Points

Opioid medications are known for their withdrawal symptoms when an individual struggling with opioid addiction stops using them. Essentially, flu-like symptoms begin to appear as the body processes the opioids out of its system. This is just one reason why you may ask how long do opioids stay in your system? Insight into this question could help prepare for the onset of withdrawal, whether coming off illicit or prescription opioids. 

Unfortunately, how long opioids will stay in your system can vary based on a wide array of factors. For one, some opioids are much longer acting than others. Additionally, each individual is unique and has biological and situational variations that will affect how the substances are processed.

Effects vs. Detection

How long the effects of a substance last are correlated, but not equal to that of how long they are present and detectable in the human body. Generally speaking, the presence of a substance may be detectable for far longer than the length of time in which the effects are felt. Consider marijuana in which the effects may only last a couple of hours, but a urine test can detect its use days later.

How long an opioid stays in your system can be estimated based on an equation using the elimination half-life – how long it takes for half of the substance to be processed and eliminated from the body. The effects of an opioid may begin to wear off when there is still 50% or more of a substance in your system.

Opioid Half-Lifes & Detection

Some opioids have vastly different half-lives than others. Heroin for example has an extremely short half-life. Suboxone and methadone, synthetic drugs that act on opioid receptors, have vastly longer half-lives. Additionally, these substances can be detected via different tests for hours or even days after use.

Substance Elimination Half-Life Saliva Test Urine Test Blood Test
Heroin 3-6 minutes 5 hrs 2-7 days 6 hrs
Fentanyl 2-4 hours 1-4 Days 8-24 hrs 12 hrs
Morphine 3-4 hours 4 days 3 days 12 hrs
Hydromorphone 2-3 hours 3-4 days 24 hrs
Methadone 15-20 hours After 30 min and Up to 2 Days After 1 hr and Up to 2 Weeks After 30 mins up to 2-3 Days
Suboxone 24 to 42 hours 3 days 6 days 2 days

Individual Variation Factors

The length of effects and detection can vary so much due to various factors that differ from person to person. Biological and situational factors that may affect how long the effects of opioids last and how long they will stay in your system include:

  • Dosage
  • Length of Use
  • Weight
  • Gender
  • Age
  • Diet
  • Water Intake
  • Kidney & Liver Health

Clearly, it could be hours or days after the last use when withdrawal symptoms could set it. Before detoxing, discuss these factors with a doctor or addiction treatment professional and develop a recovery plan.

When to Seek Help from Addiction Treatment Programs

A person doesn’t have to hit rock bottom to ask for help. If they’ve tried to quit and can’t, feel strong cravings, or go through withdrawal symptoms like fatigue or depression when not using, it’s time to consider treatment. Cocaine rehab offers tools and support to help someone regain control and build a healthier future.

Your Path to Freedom Starts Today

You don’t have to face addiction alone. Our compassionate team is ready to help you reclaim your life. Take the first step toward lasting recovery by contacting The Freedom Center today.

Amanda Stevens, B.S.

Amanda Stevens, B.S.

Medical Content Writer

Amanda Stevens is a highly respected figure in the field of medical content writing, with a specific focus on eating disorders and addiction treatment. Amanda earned a Bachelor of Science degree in Social Work from Purdue University, graduating Magna Cum Laude, which serves as a strong educational foundation for her contributions.

We Accept With Most Major Insurance

If you or a loved one is ready to get help but finances are holding you back, give us a call. We can work with your health insurance provider.

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All content produced by The Freedom Center undergoes a detailed evaluation process to ensure accuracy and quality. We only work with medical professionals and individuals with extensive experience in the field, and all content produced undergoes a review process to ensure accuracy.

Our goal is to be a reliable resource the recovery community can turn to for information they can trust.

Amanda Stevens, B.S.

Amanda Stevens, B.S.

Medical Content Writer

Amanda Stevens is a highly respected figure in the field of medical content writing, with a specific focus on eating disorders and addiction treatment. Amanda earned a Bachelor of Science degree in Social Work from Purdue University, graduating Magna Cum Laude, which serves as a strong educational foundation for her contributions.

We Accept With Most Major Insurance

If you or a loved one is ready to get help but finances are holding you back, give us a call. We can work with your health insurance provider.

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Powder cocaine is a hydrochloride salt that’s usually snorted or dissolved and injected. 

Crack cocaine is a crystalized form that’s smoked. Crack produces a faster, more intense high, but also wears off quickly, leading to more frequent use. [11]

Both forms are highly addictive, but crack is often associated with a quicker path to dependence due to how rapidly it enters the bloodstream and affects the brain.

Finishing rehab doesn’t mean the journey ends. 

At The Freedom Center, the team will help each person develop a personalized recovery plan that lasts. That might include alumni support, sober living connections, and continued therapy. 

The goal is that everyone leaves with a roadmap—and a support system—to stay sober and thrive in real life after their time at The Freedom Center.

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